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TO CURE 100 MILLION PEOPLE, THE
NUMBER OF PATIENTS DIAGNOSED
WITH FATTY LIV DISEASE, A
CONDITION CAUSED BY OBESITY.
>> IT IS A HUGE EPIDEMIC, IT HAS
NO TREATMENT AND AFFECTING MANY
PEOPLE
IT IS BECOMING THE NUMBER ONE
REASON FOR THE LIVER TRANSPLANT
IN THE U.S
AND IT IS ALL CAUSED B A ACUMEN
— AN ACCUMULATION OF FATS.
TED: THEY ARE SMALL MOLECULES
LIKE GLUCOSE AND FAT.
THERE ARE MORE THAN 100,000 IN
THE HUMAN BODY.
PIRHAJI SAYS UNDERSTANDING THE
TABLETS CAN BE KEY TO FINDING
NEW DRUGS TO TREAT LIVER DISEASE
AND MANY OTHERS.
WE SAW THE LACK OF PRECISION
MEN – PRECISION MEDICINE.
THERE ARE 70 PATIENT WITH
OBESITY AND DIABETES WHO DEVELOP
COMPLICATIONS.
SOME DEVELOP KIDNEY ISSUES, BUT
WE DO NOT HAVE DATA EVENT
APPROACH TO PREDICT WHICH AMOUNT
OF PATIENTS WILL DEVELOP WHICH
COMPLICATIONS AND HOW TO TREAT
THOSE PATIENTS.
TE WITH THIS IDEA IN MIND,
PIRHAJI FOUNDED IT REVIVE MED IN
2016.
THE CAMBRIDGE BASE STARTUP USE
MACHINE LEARNING ALGORITHM OR
ARTIFICIAL INTELLIGENCE, PIRHA
BELIEVES AI WILL SPEED THE
PROCESS OF METABOLITE KNOWLEDGE
AND DRUG DISCOVERY.
>> UNDERSTANDING METABOLITE IS
WHERE WE USED TO BE 20 YEARS AGO
FOR UNDERSTANDING DNA.
WHEN YEARS AGO, WE WERE ABLE TO
SEQUENCE A HANDFUL OF GEN AND
THAT IS WHERE WE ARE NOW FOR
METABOLITES.
THAT IS WHERE WE SAW THA
DEVELOPING, SMART ALGORITHMS TO
RESOLVE THOS AMBIGUITIES COULD
HAVE A SIGNIFICANT IMPACT.
TE MUSING OVER THAT BEGAN
WHILE PIRHAJI WAS I UNDERGRAD
— AN UNDERGRADUATE STUDENT IN
IRAN.
SHE READ ABOUT RESEARCH IN THE
TOPIC BEING DONE A M.I.T., NOT
KNOWING SHE WOULD ONE DAY
RECEIVE HER PHD FROM THE SCHOOL
AND BECOME A PIONEER IN THE
FIELD OF METABOLITE MIX.
>> I HAVE BEEN INTERESTED IN
MATHEMATICS, I STARTED GOING TO
METALS — GOING TO MEDICAL
SCHOOL BUT I LEFT MY DEGREE
BECAUSE OF MY INTEREST IN
MATHEMATICS AND I REALIZED I
COULD USE MATHEMATICS AND
COMPUTER SCIENCE AT — COMPUTER
SCIENCE AND BIOLOGY.
SINCE THEN, I HAVE BEEN
DEVELOPING ALGORITHMS TO
UNDERSTAND BIOLOGY DATA.
I’M EXCITED TO INNOVATE AND
DISRUPT, BECAUSE THE TYPE OF
WORK WE ARE DOING IS NEW.
WE PUSH THE BOUNDARIES.
TED: PIRHAJI WAS NAMED A 20 TED
FELLOW, HER COMPANY RECEIVED TWO
GOLDEN TICKET AWARDS FROM
BRISTOL-MYERS SQUIBB AND OF
ARTISTS ALLOWING HER COMPANY TO
WORK IN THE BIOTECH LAUNCHPAD
LAB CENTRAL.
FOR NOW, SHE CONTINUES TO
RESEARCH LOOKING TO DEVELOP THE
NEXT MIRACLE DRUG.
TED: >> ALL OF US HAVE THIS
VISION OF SAVING LIVES.
WE WANT TO DO A SCIENCE
APPROACH.
SHAYNA LAST YEAR, LAYLA WON AN
AWARD AND SHE RECORDED HER OWN
TED TALK.
LOOK FOR IT LATER THIS YEAR.
THAT IS "CHRONICLE" FOR TONIGHT.
THANK YOU FOR JOINING

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