Zoloft (Sertraline): What are the Side Effects? Watch Before You Start!
Get a doctors perspective on the medication Zoloft or Sertraline. Is it right for you? What side effects should you look out for? Learn about what conditions it works …
Are you or a loved one suffering from depression
Has your doctor recommended you take Zoloft
or the generic version Sertraline?
Are you concerned about possible side effects?
If so then this is the video for you.
Keep watching to learn a little more about
what to watch out for and how this medication
can be a help to you.
Welcome to Family Med, I'm Dr. Richardson
and this is your home for practical and accurate
information to help your family make healthy
This is the channel that focuses on bringing
better health to your home.
On today's episode we are going to be going
over a common antidepressant named Sertraline
or more commonly referred to as Zoloft.
Sertraline is the generic version of Zoloft
which has been around in the United States
Zoloft is a medication that is used most commonly
to treat clinical depression and anxiety but
is also commonly used to treat conditions
such as Obsessive Compulsive disorder, PTSD,
and severe PMS.
It's in the class of medications that we call
SSRI's or Selective Serotonin Reuptake Inhibitors.
These are a group of medications that target
the hormone Serotonin and help decrease how
rapidly it is broken down in the nerves thus
keeping your serotonin levels higher.
It's one of the vital chemicals or neurotransmitters
that help regulate a lot of the functions
of the body like mood, social behavior, appetite
and digestion, sleep, memory among other things.
It is one of the chemicals that plays a big
role in depression and anxiety and your overall
When you are suffering from depression or
anxiety or the other conditions that I mentioned
earlier, in addition to things like eating
healthy and exercise, counseling and therapy
and getting plenty of sleep, targeting these
chemicals in the brain has been found to be
very helpful in allowing people to resume
a normal life when they are battling with
You don't have to live with these conditions
controlling your life.
Go see your doctor so you can get an accurate
diagnosis and figure out a good treatment
plan for you.
Remember depression, anxiety, PTSD, OCD and
any other mental health disease are as real
of a medical condition as diabetes or high
blood pressure and you shouldn't feel any
different about treating these conditions
than you would any other disease.
Ok, so you've talked to your doctor and you
both have decided that for your symptoms Zoloft
is going to part of your treatment plan.
What should you expect?
Well, first of all it comes in a pill at doses
of 25, 50 and 100mg.
The most common doses range from 50mg to over
200mg in some people.
It's important to remember that this is the
kind of medication that you need to take daily
if you are going to be on it.
Most people will start to notice some difference
within 1-2 weeks but it typically doesn't
reach its full effect for 4-6 weeks.
So, you should be following up with your doctor
within 2-4 weeks after starting on it to report
on how things are working.
If you are going to be taking it, you want
to make sure that you are not missing a lot
Doing so can really affect how well it's going
to work and increase your risk of having side
Also, unless you're having some significant
problems with the medication, especially after
being on it a few weeks, you don't want to
stop this medication abruptly.
After being on it for a while your brain gets
used to a certain level of the Serotonin and
stopping it quickly will really throw you
off and make you feel bad.
Most doctors recommend that, if the medication
is working well, you take it for at least
6 months before you think about stopping it.
Stopping it sooner than that, because you
feel like your depression or anxiety is gone,
increases your risk for having your symptoms
If you feel like it is something that is making
a big difference in your life and you want
to continue on it longer than the 6 months
then it is safe to do so.
I have patients that have decided that they
need to stay on it for years and that works
So what kind of side effects should you look
Well, as with any medication you can find
a big list of side effects that will be listed
in the paperwork from your pharmacist.
Sometimes these lists can be intimidating
but in the case of Zoloft it is generally
I rarely have patients on it that want to
stop due to significant side effects.
However, any medication has the potential
to having some side effects.
Some common ones that are possible would be
some headaches, nausea, tiredness or difficulty
sleeping, some dry mouth, constipation or
diarrhea, heartburn or abdominal pain.
These types of symptoms tend to be short lived
in most people and often times, by modifying
when you take it or by taking it with food
you can improve or even avoid a lot of them.
Usually with time, they start to get better
on their own.
One area that concerns a lot of people is
the effect that antidepressants can have on
your intimate relations.
This can be a known problem with most antidepressants,
and certainly Zoloft can be one of them.
It doesn't happen to everybody but it is not
This probably one of the more common reasons
that patients will come back asking to try
If it is working for your other symptoms though
don't despair because there are some things
we can do to work with the problem, so don't
stop it until you talk to your doctor if that
is a concern.
Probably the most common reason I have somebody
stop this or any antidepressant medication
though is that they "didn't like the way it
made them feel".
It may help with their depression or anxiety,
so they don't feel sad anymore, but they don't
feel happy either.
That certainly isn't the goal of this kind
Our goal is to help lift you up out of the
hole you are in and help you see that life
is doable again.
If we turn you into a zombie and you are neither
happy or sad we aren't doing you any favors.
We still want you to be happy when you are
supposed to be happy and sad when your supposed
to be sad.
So if you are noticing things like that then
talk to your doctor about other options that
are out there.
There are some rare side effects that you
need to pay more close attention to though.
This is not an exhaustive list, however it's
important to know that first, all antidepressant
medication including sertraline have the risk
of making your symptoms worse at first.
You may be feeling really down right now,
but if all of a sudden your depression and
anxiety get worse or you start having suicidal
thoughts you need to be in contact with your
doctor and get help.
I always recommend when starting these kinds
of medications that you confide in somebody
you trust and tell them that you are taking
Let them know about these risks so they can
help you recognize what is happening and assist
you in getting the help you need.
Other rare side effects can be certain heart
arrythmias, an increased risk of bleeding,
electrolyte disturbances, liver problems,
allergic reactions and something called Serotonin
syndrome where your body gets too much serotonin.
This is very rare but can present with symptoms
like agitation, confusion, rapid heart rate
and high blood pressure, dilated pupils, loss
of muscle coordination, muscle rigidity, diarrhea
and heavy sweating.
If you think this is happening to you, get
into your doctor or the emergency room right
The worst part about discussing the side effects
of medications is scaring you away from taking
It's important to keep the perspective that
the vast majority of people taking sertraline
do really well with minimal to no side effects.
So, if you are deciding to not take a medication
like this due to a fear of having a very rare
side effect, you can potentially be robbing
yourself from an important tool in treating
Remember it's important to keep the perspective
that if you are having a problem with the
medication, you don't need to stay on it.
There are a lot of other options out there
so get with your doctor and talk to them about
Depression/anxiety and other mental health
conditions can be very debilitating.
They are as real as any other medical condition
When you have a true clinical depression taking
something like Zoloft can be a life altering
I'm always amazed at what a significant difference
this medication has had in the life of my
It's certainly not for everybody and yes there
are other nonmedication options out there
that may work for you.
If, however, you and your doctor feel that
this is the best option for your treatment
plan you now have a good foundation of knowledge
of what to expect and what kind of side effects
to watch for.
Having that information can be really powerful
in your life.
This is not an all-inclusive discussion of
My purpose in sharing this information is
to help give information that you can think
about and discuss with your own doctor.
It's not meant to give you direct medical
advice in your own personal situation.
So, take this information and discuss it with
your own doctor.
Overall, I hope you have found this information
to be helpful especially in taking away some
of the stigma that surrounds taking medication
for mental health issues.
To keep learning about other aspects of your
health check out my other videos.
To learn about whether another antidepressant
named Lexapro is for you click here.
To find out about simple ways to save a lot
of money on your healthcare click here.
Go ahead and subscribe and let me know what
you think in the comments below.
Until next time, this FamilyMed with Dr. Richardson
and remember to take care of your body because
it's the only one you have.